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A highly potent serum with a silky, luxurious Texture to smooth even the most stubborn, deep-set lines, wrinkles and creases, including marionette lines, frown lines, smile lines and nasolabial folds.

What It Is

Essential Fx Acyl-Glutathione Deep Crease Serum is designed to target the most stubborn deep-set lines, creases and wrinkles, including deep forehead wrinkles.

This intensely hydrating deep wrinkle serum is formulated with Acyl-Glutathione to help reduce the look of deep wrinkles and creases by protecting and replenishing skin. Imperfections appear shallower and expression lines appear erased while a Vitamin F Blend restores suppleness by visibly improving the skin’s moisture barrier.

What It Does

  • Softens the look of facial lines from daily repetitive movements.
  • Visibly improves etched creases making them appear more shallow.
  • Minimises the appearance of skin imperfections and imparts a beautiful radiance.

What To Expect
Due to the science and compounds used in our products the feel and Scent may vary.

Texture: Serum

Consistency: Lightweight

Scent: Natural, Aromatic

* This product is free from soy, nuts, gluten, fish, milk, corn, phthalates, sulfates, parabens, talc, and mineral oil. Cruelty-free.

CONSUMER RESULTS*

Overall Skin Condition

93% noticed skin looked renewed 84% saw that skin looked more toned

Advanced Claims

89% noticed an improvement in lines & texture
86% felt firmer, tighter skin
86% saw an improvement in expression lines
84% saw that wrinkles were smoothed
83% noticed creases appeared shallower & forehead lines appeared smoother
82% saw tighter-looking skin
80% saw lines smoothed around the mouth & lips
79% noticed engraved imperfections appeared shallower
77% noticed that skin looked lifted
74% felt that skin looked dramatically younger
73% saw that deep-set wrinkles, including marionette lines & nasolabial folds were smoothed
*Based on a consumer perception study on 102 women over 28 days

Acyl-Glutathione: The Master Antioxidant

Comprised of three amino acids, Glutathione is the body's main antioxidant and helps to reduce the look of deep creases and improve fragile skin by protecting, repairing and detoxifying. Fat-soluble for maximum stability and penetration.

Vitamin F Blend: Ultimate Moisture Barrier Protection

Flaxseed, chia seed and macadamia seed oils restore suppleness and create a healthy glow by intensely moisturising and improving skin's moisture barrier. Essential yet not naturally found in the human body.

Ingredients:

Water/Aqua/Eau, Propanediol, Squalane, Hydrogenated Polyisobutene, S-Palmitoylglutathione, Dimethicone, Glycerin, Macadamia Ternifolia Seed Oil, Xylitylglucoside, Tetrahexyldecyl Ascorbate, Dimethyl MEA, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Anhydroxylitol, Lactic Acid, Xylitol, Xanthan Gum, Linum Usitatissimum (Linseed) Seed Oil, Salvia Hispanica Seed Oil, Tocopherol, Ethylhexylglycerin, Magnesium Aspartate, Zinc Gluconate, Alaria Esculenta Extract, Glucose, Sodium Hyaluronate, Copper Gluconate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Magnesium Chloride, Caprylic/Capric Triglyceride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl/Capryl Glucoside, Caprylyl Glycol, Potassium Sorbate, Phenoxyethanol, Fragrance/Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool.

Range:
Essential FX Collection
Brand:
Perricone MD
Volume:
1 fl.oz / 30ml
Directions:

Massage onto cleansed face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favourite Perricone MD Moisturiser. Use morning and evening.

Essential Fx Acyl-Glutathione Deep Crease Serum

An intense, moisturising serum with a blend of vitamin F for deep lines and wrinkles, including the corner of the mouth, frown lines and smile lines.

GBP 133.0

£133.00

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A highly potent serum with a silky, luxurious Texture to smooth even the most stubborn, deep-set lines, wrinkles and creases, including marionette lines, frown lines, smile lines and nasolabial folds.

What It Is

Essential Fx Acyl-Glutathione Deep Crease Serum is designed to target the most stubborn deep-set lines, creases and wrinkles, including deep forehead wrinkles.

This intensely hydrating deep wrinkle serum is formulated with Acyl-Glutathione to help reduce the look of deep wrinkles and creases by protecting and replenishing skin. Imperfections appear shallower and expression lines appear erased while a Vitamin F Blend restores suppleness by visibly improving the skin’s moisture barrier.

What It Does

  • Softens the look of facial lines from daily repetitive movements.
  • Visibly improves etched creases making them appear more shallow.
  • Minimises the appearance of skin imperfections and imparts a beautiful radiance.

What To Expect
Due to the science and compounds used in our products the feel and Scent may vary.

Texture: Serum

Consistency: Lightweight

Scent: Natural, Aromatic

* This product is free from soy, nuts, gluten, fish, milk, corn, phthalates, sulfates, parabens, talc, and mineral oil. Cruelty-free.

CONSUMER RESULTS*

Overall Skin Condition

93% noticed skin looked renewed 84% saw that skin looked more toned

Advanced Claims

89% noticed an improvement in lines & texture
86% felt firmer, tighter skin
86% saw an improvement in expression lines
84% saw that wrinkles were smoothed
83% noticed creases appeared shallower & forehead lines appeared smoother
82% saw tighter-looking skin
80% saw lines smoothed around the mouth & lips
79% noticed engraved imperfections appeared shallower
77% noticed that skin looked lifted
74% felt that skin looked dramatically younger
73% saw that deep-set wrinkles, including marionette lines & nasolabial folds were smoothed
*Based on a consumer perception study on 102 women over 28 days

Acyl-Glutathione: The Master Antioxidant

Comprised of three amino acids, Glutathione is the body's main antioxidant and helps to reduce the look of deep creases and improve fragile skin by protecting, repairing and detoxifying. Fat-soluble for maximum stability and penetration.

Vitamin F Blend: Ultimate Moisture Barrier Protection

Flaxseed, chia seed and macadamia seed oils restore suppleness and create a healthy glow by intensely moisturising and improving skin's moisture barrier. Essential yet not naturally found in the human body.

Ingredients:

Water/Aqua/Eau, Propanediol, Squalane, Hydrogenated Polyisobutene, S-Palmitoylglutathione, Dimethicone, Glycerin, Macadamia Ternifolia Seed Oil, Xylitylglucoside, Tetrahexyldecyl Ascorbate, Dimethyl MEA, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Anhydroxylitol, Lactic Acid, Xylitol, Xanthan Gum, Linum Usitatissimum (Linseed) Seed Oil, Salvia Hispanica Seed Oil, Tocopherol, Ethylhexylglycerin, Magnesium Aspartate, Zinc Gluconate, Alaria Esculenta Extract, Glucose, Sodium Hyaluronate, Copper Gluconate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Magnesium Chloride, Caprylic/Capric Triglyceride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl/Capryl Glucoside, Caprylyl Glycol, Potassium Sorbate, Phenoxyethanol, Fragrance/Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool.

Range:
Essential FX Collection
Brand:
Perricone MD
Volume:
1 fl.oz / 30ml
Directions:

Massage onto cleansed face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favourite Perricone MD Moisturiser. Use morning and evening.

Customer Reviews

Overall Rating : 3.91 / 5 (67 Reviews)
  • 37 5 star reviews
  • 9 4 star reviews
  • 8 3 star reviews
  • 4 2 star reviews
  • 9 1 star reviews
See all reviews
 

Top Customer Reviews

Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are independent and do not represent the views of The Hut Group.

Great product

I do love this serum. It definitely makes a difference; one of the only products that helps with marionette lines. It is a bit too expensive for me. I ordered it when I got a good discount ( 1/2 off). I don't think I'll be ordering it again until that discount as available again because I cannot afford it.

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Reliable Product

Perricone MD always provides Great products that are Very Reliable. The Deep Crease Serum has worked wonders on what used to be "deep creases" on my face! The key is to use it Daily! Works Great!

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Magic

I am so impressed with this deep crease serum, for me, it exceeded my hopes and expectations. I have been forming fine lines across my forehead from repetitive motions and stress!) and have been watching them grow deeper and spread further over time. I have tried other products with mild results, but this is the first serum that I have ever used where I can say that I actually see a significant difference in my skin. For the past month I have incorporated this serum every night as part of my PM skincare routine and the lines are not only fading, but some have actually disappeared... this stuff is magic! At first I only was using two drops on my forehead, but now I also use a drop on my smile lines and across the horizontal lines on my neck. I am so incredibly pleased with my results so far, I look forward to continued improvement of my skin with daily use. The price may be steep, but you truly use so little at a time and the results are noticeable and very real.

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Small reduction

Used over the past month, twice a day. Small reduction in my major forehead creases.

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The best serum ever

You would look at women posting their before and after pics and wonder about the depth of their facial creases, their age, life style, nutrition as a factors influencing wrinkles formation and leave the web site in disbelieve I am asking you to believe me cause:I am 62, watching what I am eating, working my sweat by gardening and walking, taking my supplements.Never developed habit of using the sun screamDeveloped deep creases or so cold smile wrinkles long time ago. I thought it was it.Bought the first Dr Perricone book 3 years ago and started using his cream and serum 3 years ago1 year Ago he came up with the new line of Fox essential glutathione eye and deep creases cerium, creams and so onStarted using his deep crease Fx glutathione in January not even twice per day, just at night timeI am telling the truth: my absolutely deep crease on the left side disappeared completely in April and the left side became much superficial by nowI LOVE Dr Perricone and what he does for female not only beauty but self esteem and moodHe definitely knows what woman wants 

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Love This Cream!

Got it in a kit! I completely changed over my skincare products from another company to Perricone MD after they allowed afterpay and klarna. I have been wanting to for awhile but couldn't afford the money all at once. Now I can. I got one half ounce with two other products. Been using for about a month. I only use it on my lines and wrinkles. Not my full face. For me, it works. On my forehead, and all around my mouth the lines are going away! When I run out, will buy the full size. This is the only skincare I have ever used that actually does what it says it's going to do! I've had good skincare,just not as good as this! Won't go back.

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Good name for product

Good product, does seem to help with marionette lines and lip lines.

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Not working

Its been 10 days since I started using it every morning and evening, sometimes more in the afternoon but havent seen any results or improvement on my skin. I have a shallow wrinkle alongside my mouth and the serum doesnt fade it. With that price, I expected it works after few days of using as I know my skin well, If anything works on my skin, i will see results immediately, I mean I can feel it right at the first time I put on my skin, but if I dont feel anything I know nothing is coming. 

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I loved it

The results were immediate.

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I hope to never be without this.

Taking advantage of the great deals that occur on this website, I have a variety of the serums, Sub D, moisturizers and use them in different combinations. At 68, I'm loving my skin. When I added the Deep Crease Serum to the areas in need, I really saw a marked improvement. Auto Replenishment, check!

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