Skip to content

Blemish Relief

Blemish Relief 90-Day Regimen

SKU: 90602


A simple, two-step skincare system that works with your skin's natural microbiome to target and safely, yet effectively, treat the three causes of blemishes.

Decrease Quantity Increase Quantity

Buy It Now

What It Is

Perricone MD Blemish Relief Prebiotic Therapy is a simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently & effectively treat & prevent the most troublesome blemishes, while restoring & maintaining a healthy skin balance, for clearer, blemish-free skin. This powerful 2-step regimen is clinically proven to be non-irritating & will not strip or over-dry skin.


What It Does

  • Thoroughly cleanses, reduces excess oil, unclogs pores.
  • Eliminates debris without irritating sensitive, blemish-prone skin.
  • Gently kills blemish-causing bacteria.
  • Hydrates, soothes and visibly reduces redness.
  • Helps to heal blemishes while you sleep without over-drying the skin.

What To Expect








Gentle & Soothing Cleanser

Use this cleanser both morning and night to thoroughly cleanse, reduce excess oil, unclog pores and eliminate debris without irritating sensitive, blemish-prone skin.


Calming Treatment & Hydrator

After cleansing in the morning, apply this lightweight lotion to gently provide support for oily and blemish-prone skin, while nourishing with essential hydration.


Retinol Treatment & Moisturiser

After cleansing at night, apply this nourishing moisturiser to help control excess oil and improve the appearance of skin while you sleep without over-drying.

Understand the science and benefits behind creating a healthy microbiome and balanced skin.

The science behind Blemish Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome to target troublesome blemishes. Using naturally occurring prebiotics, Blemish Relief helps your skin fight back against blemishes without disrupting its natural balance. The result? An effective defense against blemish-causing bacteria that promotes a clear, blemish-free complexion.

Below are some of the key ingredients in Blemish Relief behind our prebiotic approach:


Sucrose is made from ultra-fine sugar and is a mild exfoliant that helps unclog pores and remove excess dirt and oil without over-drying or stripping skin. Sucrose helps support a healthy skin microbiome by encouraging good bacteria. It rinses off quickly and easily, making it ideal for gentle yet effective cleansing.


Citrulline, first discovered in watermelon, is an alpha-amino acid that visibly calms skin for a clearer, more even-looking complexion. Nourishing and soothing, it is an ideal way to counteract the drying effect of anti-blemish ingredients.


Lactic & Succinic Acids are short chain fatty acids help quickly shrink blemishes by working alongside salicylic acid to attack blemish-causing bacteria and encourage good bacteria necessary for a healthy microbiome. They also provide gentle yet effective exfoliation for smoother, more even-looking skin.


Niacinamide, also known as Vitamin B3, is found in foods such as tomatoes. This skin-clearing powerhouse helps to gently and visibly erase imperfections, unclog oily pores, and minimise the redness and uneven tone that can be left behind after breakouts by improving skin’s moisture barrier.


Squalane is found naturally in the human body but also can be derived from olive oil. It hydrates skin without making it look or feel greasy. This lightweight hydration is ideal for oil and blemish prone skin as it helps maintain optimal hydration without clogging pores or causing blemishes.


Salicylic Acid is a beta-hydroxy acid and is considered the best non-prescription treatment for blemish and oil-prone skin. It quickly and effectively exfoliates and removes dead skin which can clog pores and cause breakouts. Because it is oil-soluble, salicylic acid is easily absorbed for targeted, more effective treatment.


Retinol is and ultra-powerful, non-prescription Vitamin-A derivative that helps prevent breakouts by unclogging pores and accelerating surface skin exfoliation and renewal. Unique slow-release carrier system helps preserve this unstable ingredient and calm skin.


Gentle & Soothing Cleanser

Active ingredient: Salicylic Acid 2.0%. Inactive Ingredients: Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Sil- ylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Calming Treatment & Hydrator

Active ingredient: Salicylic Acid 0.5%. Inactive Ingredients: Water/Aqua/Eau, SD Alco- hol 40-B, Glycerin, C12-15 Alkyl Lactate, PVP, Di- methicone, Polysorbate 20, Citrulline, Squalane, Lactic Acid, Succinic Acid, Polyacrylamide, Dimeth- icone/Vinyl Dimethicone Crosspolymer, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Retinol Treatment & Moisturizer

Active ingredient: Salicylic Acid 0.5%. Inactive Ingredients: Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, Dicaprylyl Ether, Niacinamide, Cit- rulline, Arginine, Methyl Gluceth-20, Cetearyl Alco- hol, Carbomer, Xanthan Gum, Tocopheryl Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate, Glyceryl Stearate, Methyl Glu- cose Sesquistearate, Polysorbate 20, Phenoxy- ethanol, Sodium Benzoate, Potassium Sorbate

Gentle & Soothing Cleanser - Step 1: Day & Night

Lather a quarter-sized amount in hands & gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with BLEMISH RELIEF Calming Treatment & Hydrator in the morning & BLEMISH RELIEF Retinol Treatment & Moisturiser in the evening.


Calming Treatment & Hydrator - Step 2: Day

Shake well. Apply a thin, even layer to skin in the morning. For best results, use after cleansing with BLEMISH RELIEF Gentle & Soothing Cleanser.


Retinol Treatment & Moisturiser - Step 2: Night

Shake well. Apply a thin, even layer to skin in the evening. For best results, use after cleansing with BLEMISH RELIEF Gentle & Soothing Cleanser.


You may also like

Recently viewed